๐ ๐ฑ๐ฟ๐๐ด’๐ ๐ฒ๐ณ๐ณ๐ฒ๐ฐ๐ ๐ถ๐ ๐ฑ๐ฒ๐ฐ๐ถ๐ฑ๐ฒ๐ฑ ๐ฏ๐ ๐ฒ๐น๐ฒ๐ฐ๐๐ฟ๐ผ๐ป๐. ๐ ๐ผ๐๐ ๐ฐ๐น๐ฎ๐๐๐ถ๐ฐ๐ฎ๐น ๐๐ผ๐ผ๐น๐ ๐ฐ๐ฎ๐ป’๐ ๐๐ฒ๐ฒ ๐๐ต๐ฒ๐บ ๐ฐ๐น๐ฒ๐ฎ๐ฟ๐น๐.
Every drug on a pharmacy shelf took 10โ15 years and over $2.5B to develop โ much of it spent estimating how tightly a molecule binds its protein target. For most drugs, classical methods handle this well. But for metalloenzymes โ… Read More »๐ ๐ฑ๐ฟ๐๐ด’๐ ๐ฒ๐ณ๐ณ๐ฒ๐ฐ๐ ๐ถ๐ ๐ฑ๐ฒ๐ฐ๐ถ๐ฑ๐ฒ๐ฑ ๐ฏ๐ ๐ฒ๐น๐ฒ๐ฐ๐๐ฟ๐ผ๐ป๐. ๐ ๐ผ๐๐ ๐ฐ๐น๐ฎ๐๐๐ถ๐ฐ๐ฎ๐น ๐๐ผ๐ผ๐น๐ ๐ฐ๐ฎ๐ป’๐ ๐๐ฒ๐ฒ ๐๐ต๐ฒ๐บ ๐ฐ๐น๐ฒ๐ฎ๐ฟ๐น๐.









